CHIR98014(CT98014)/
Cat.No.ABP000489
Chemical NameCHIR98014(CT98014)/
CAS252935-94-7
MolFormulaC20H17Cl2N9O2
MolWeight486.314
Purity 98%
Chemical Name : CHIR98014(CT98014)/
CAS : 252935-94-7
Synonyms: N6-[2-((4-(2,4-dichlorophenyl)-5-(1H-imidazol-2-yl)-2-pyrimidinyl)amino)- Ethyl]-3-nitro-2,6-pyridinediamine
Biologieal
Very potent, selective, cell-permeable reversible inhibitors (INHs) of GSK-3; highly recommended tool.
Reference
SE Nikoulina et al. Inhibition of Glycogen Synthase Kinase 3 Improves Insulin Action and Glucose Metabolism in Human Skeletal Muscle. Diabetes 2002, 51(7), 2190-2198. [online] DB Ring et al. Selective glycogen synthase kinase inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes 52: 588
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