CHIR98014(CT98014)/

生物活性

Very potent, selective, cell-permeable reversible inhibitors (INHs) of GSK-3; highly recommended tool.

参考文献

SE Nikoulina et al. Inhibition of Glycogen Synthase Kinase 3 Improves Insulin Action and Glucose Metabolism in Human Skeletal Muscle. Diabetes 2002, 51(7), 2190-2198. [online] DB Ring et al. Selective glycogen synthase kinase inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes 52: 588