501925-31-1

溶解度:Unknown

储存条件:at -20℃ 2 years

生物活性

Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors (EC₅₀ = 216 nM), with no detectable effect on α4β2, α3β4 and α9α10 receptors. Active in vivo following systemic administration

参考文献

Hurst et al (2005) A novel positive allosteric modulator of the a7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization. J.Neurosci. 25 4396.