501925-31-1

Storage:at -20℃ 2 years

Biologieal

Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors (EC₅₀ = 216 nM), with no detectable effect on α4β2, α3β4 and α9α10 receptors. Active in vivo following systemic administration

Reference

Hurst et al (2005) A novel positive allosteric modulator of the a7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization. J.Neurosci. 25 4396.