153436-54-5
![4-[(3-溴苯基)氨基]-6,7-二甲氧基喹啉](https://stcdn.activebiopharma.com/active/ABP000869.png)
153436-54-5
编号ABP000869
化学名称4-[(3-溴苯基)氨基]-6,7-二甲氧基喹啉
英文名称 PD153035 hydrochloride/
MDL: MFCD01074805
分子式C16H14BrN3O2.ClH
分子量396.671
纯度 >99%
化学名称 : 4-[(3-溴苯基)氨基]-6,7-二甲氧基喹啉
CAS : 153436-54-5
英文名称: PD153035 hydrochloride/
英文同义词: PD 153035 HYDROCHLORIDE
溶解度:Soluble in DMSO at 10 mmol/L
储存条件:-20C 2 years
生物活性
Pazopanib (GW-786034) is a second-generation multitargeted tyrosine kinase inhibitor against VEGFR-1, 2 and 3, platelet-derived growth factor receptor (PDGFR)-, PDGFR-ß and c-kit.
参考文献
1. Pazopanib, a potent orally administered small-molecule multitargeted tyrosine kinase inhibitor for renal cell carcinoma. Sonpavde, G., Hutson, T.E., et al. Volume 17, Issue 2, February 2008, Pages 253-261
2. Pazopanib: a novel multitargeted tyrosine kinase Inhibitor. Guru Sonpavde, Thomas E. Hutson. 2007 Current Oncology Reports 9 (2), pp. 115-119
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ABT-869(Linifanib)/AL-39324,RG3635/
796967-16-3
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苹果酸舒尼替尼
341031-54-7
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拉帕替尼
388082-78-8
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CHIR-258(Dovitinib)
405169-16-6
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