153436-54-5

Solubility:Soluble in DMSO at 10 mmol/L

Storage:-20C 2 years

Biologieal

Pazopanib (GW-786034) is a second-generation multitargeted tyrosine kinase inhibitor against VEGFR-1, 2 and 3, platelet-derived growth factor receptor (PDGFR)-, PDGFR-ß and c-kit.

Reference

1. Pazopanib, a potent orally administered small-molecule multitargeted tyrosine kinase inhibitor for renal cell carcinoma. Sonpavde, G., Hutson, T.E., et al. Volume 17, Issue 2, February 2008, Pages 253-261

2. Pazopanib: a novel multitargeted tyrosine kinase Inhibitor. Guru Sonpavde, Thomas E. Hutson. 2007 Current Oncology Reports 9 (2), pp. 115-119