AG13958
AG13958
编号ABP000877
化学名称AG13958
CAS319460-94-1
分子式C26H22FN7O
分子量467.4976
纯度 98%
化学名称 : AG13958
CAS : 319460-94-1
英文名称: AG13958
英文同义词: N-[2-Fluoro-5-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]amino]phenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide
溶解度:Unknown
储存条件:at -20℃ 2 years
生物活性
SU5402 is a multiple target inhibitor of VEGFR2 (Flk-1/KDR) and FGFR1 (IC50 at 20 and 30 nM,respectively). This agent inhibits PDGFRβ and EGFR with IC50 values of 510 nM and > 100 μM, respectively. [1]SU 5402 inhibits tyrosine phosphorylation of VEGFR2 and PDGFR in NIH 3T3 cells with IC50 values of 0.4 and 60.9 μM, respectively. This agent inhibits embryonic left-right determination and exhibits potent anticancer activity in vitro and in vivo.
参考文献
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Pazopanib/GW-786034
444731-52-6
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![4-[(3-溴苯基)氨基]-6,7-二甲氧基喹啉](https://stcdn.activebiopharma.com/active/ABP000869.png)
4-[(3-溴苯基)氨基]-6,7-二甲氧基喹啉
153436-54-5
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Lapatinib
231277-92-2
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![4-[3-氯-4-(环丙基氨基羰基)氨基苯氧基]-7-甲氧基-6-喹啉甲酰胺](https://stcdn.activebiopharma.com/active/ABP000857.png)
4-[3-氯-4-(环丙基氨基羰基)氨基苯氧基]-7-甲氧基-6-喹啉甲酰胺
928326-83-4
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