10-炔丙基-10-去氮杂氨基蝶呤

溶解度:Unknown

储存条件:at -20℃ 2 years

生物活性

Pralatrexate is an antifolate, and structurally a folate analog. It acts as an inhibitor of dihydrofolate reductase. It is selective for the reduced folate carrier type 1. Its IC50 is < 300 nM in some cell lines. [1]

参考文献

[1] http://en.wikipedia.org/wiki/Pralatrexate