Pralatrexate(Folotyn)/

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Pralatrexate(Folotyn)/

Pralatrexate(Folotyn)/

Cat.No.ABP000543 Chemical NamePralatrexate(Folotyn)/ CAS146464-95-1 MDL: MFCD00920897 MolFormulaC23H23N7O5 MolWeight477.479 Purity >99%

Chemical Name : Pralatrexate(Folotyn)/

CAS : 146464-95-1

Synonyms: 10-PROPARGYL-10-DEAZAAMINOPTERIN

Storage:at -20℃ 2 years

Biologieal

Pralatrexate is an antifolate, and structurally a folate analog. It acts as an inhibitor of dihydrofolate reductase. It is selective for the reduced folate carrier type 1. Its IC50 is < 300 nM in some cell lines. [1]

Reference

[1] http://en.wikipedia.org/wiki/Pralatrexate

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