Pralatrexate(Folotyn)/
Cat.No.ABP000543
Chemical NamePralatrexate(Folotyn)/
CAS146464-95-1
MDL: MFCD00920897
MolFormulaC23H23N7O5
MolWeight477.479
Purity >99%
Chemical Name : Pralatrexate(Folotyn)/
CAS : 146464-95-1
Synonyms: 10-PROPARGYL-10-DEAZAAMINOPTERIN
Storage:at -20℃ 2 years
Biologieal
Pralatrexate is an antifolate, and structurally a folate analog. It acts as an inhibitor of dihydrofolate reductase. It is selective for the reduced folate carrier type 1. Its IC50 is < 300 nM in some cell lines. [1]
Reference
[1] http://en.wikipedia.org/wiki/Pralatrexate
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GSK189254
945493-87-8
-
Org 25935
949588-40-3
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MLN9708,MLN-9708,MLN 9708/
1201902-80-8
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GR 103691/
162408-66-4
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