10-炔丙基-10-去氮杂氨基蝶呤
编号ABP000543
化学名称Pralatrexate(Folotyn)/
CAS146464-95-1
MDL: MFCD00920897
分子式C23H23N7O5
分子量477.479
纯度 >99%
化学名称 : 10-炔丙基-10-去氮杂氨基蝶呤
CAS : 146464-95-1
英文名称: Pralatrexate(Folotyn)/
英文同义词: 10-PROPARGYL-10-DEAZAAMINOPTERIN
溶解度:Unknown
储存条件:at -20℃ 2 years
生物活性
Pralatrexate is an antifolate, and structurally a folate analog. It acts as an inhibitor of dihydrofolate reductase. It is selective for the reduced folate carrier type 1. Its IC50 is < 300 nM in some cell lines. [1]
参考文献
[1] http://en.wikipedia.org/wiki/Pralatrexate
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