98418-47-4

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Metroprolol succinate/

98418-47-4

Cat.No.ABP000757 Chemical NameMetroprolol succinate/ MDL: MFCD07391179 MolFormula2C15H25NO3.C4H6O4 MolWeight652.82

Chemical Name : Metroprolol succinate/

CAS : 98418-47-4

Synonyms: METOPROLOL SUCCINATE

Solubility:Soluble to 100 mM in DMSO and to 100 mM in ethanol

Storage:Store at +4℃ 2 years

Biologieal

GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation. Also reduces in vitro migration of metastatic human breast cancer cells.
 

Reference

Zhang et al (2007) Small-molecule synergist of the Wnt/β-catenin signaling pathway. Proc.Natl.Acad.Sci.USA 104 7444.

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