Chemical Name : MC1568/MC-1568
CAS : 852475-26-4
Synonyms: 3-[5-(3-(3-Fluorophenyl)-3-oxopropen-1-yl)-1-methyl-1h-pyrrol-2-yl]-n-hydroxy-2-propenamide;MC1568
Solubility:DMSO
Storage:at -20
Biologieal
MC1568 is a potent selective class II (IIa) histone deacetylas (HDAC II) inhibitor (IC50 of a maize deacetylase HD2 at 22.0 µM). MC1568 had no or a weak effect on the class I HDACs. MC1568 shows no inhibitory activity against HDAC1 but was able to inhibit HDAC4. [1, 2]
Reference
[1] Duong V et al. Mol Cancer Res. 2008 Dec; 6(12):1908-19