852475-26-4
852475-26-4
Cat.No.ABP000149
Chemical NameMC1568/MC-1568
英文名称 MC1568/MC-1568
MDL: MFCD16875423
MolFormulaC17H15FN2O3
MolWeight314.315
Purity >99%
Chemical Name : MC1568/MC-1568
CAS : 852475-26-4
英文名称: MC1568/MC-1568
英文同义词: 3-[5-(3-(3-Fluorophenyl)-3-oxopropen-1-yl)-1-methyl-1h-pyrrol-2-yl]-n-hydroxy-2-propenamide;MC1568
溶解度:DMSO
储存条件:at -20
生物活性
MC1568 is a potent selective class II (IIa) histone deacetylas (HDAC II) inhibitor (IC50 of a maize deacetylase HD2 at 22.0 µM). MC1568 had no or a weak effect on the class I HDACs. MC1568 shows no inhibitory activity against HDAC1 but was able to inhibit HDAC4. [1, 2]
参考文献
[1] Duong V et al. Mol Cancer Res. 2008 Dec; 6(12):1908-19
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