79874-76-3
Cat.No.ABP000988
Chemical NameDelmopinol
MDL: MFCD00869129
MolFormulaC16H33NO2
MolWeight271.4387
Purity 98%
Chemical Name : Delmopinol
CAS : 79874-76-3
Synonyms: 2-(3-(4-propylheptyl)morpholino)ethanol
Solubility:DMSO
Storage:at -20℃ 2 years
Biologieal
Selective RAF inhibitor, showing strong selectivity for RAF kinases among a panel of 150 tested kinases; IC50 values: ca 30 nM for BRAF V600E and wild-type CRAF and 100 nM for wild-type BRAF.Reference
C Montagut et al. Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma. Cancer Res. 2008, 68(12), 4853–4861.-
MLN2238,MLN 2238,MLN-2238/
1072833-77-2
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