
Chemical Name : Delmopinol
CAS : 79874-76-3
英文名称: Delmopinol
英文同义词: 2-(3-(4-propylheptyl)morpholino)ethanol
Synonyms: 2-(3-(4-propylheptyl)morpholino)ethanol
Solubility:DMSO
Storage:at -20℃ 2 years
Biologieal
Selective RAF inhibitor, showing strong selectivity for RAF kinases among a panel of 150 tested kinases; IC50 values: ca 30 nM for BRAF V600E and wild-type CRAF and 100 nM for wild-type BRAF.Reference
C Montagut et al. Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma. Cancer Res. 2008, 68(12), 4853–4861.
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