
Chemical Name : SB408124/SB-408124/
CAS : 288150-92-5
Synonyms: N-(6,8-Difluoro-2-methyl-4-quinolinyl)-N'-[4-(dimethylamino)phenyl]urea
Solubility:Soluble to 100 mM in DMSO
Storage:Store at RT
Biologieal
Selective non-peptide orexin OX1 receptor antagonist (Kb values are 21.7 and 1405 nM for human OX1 and OX2 receptors respectively). Blocks orexin-A induced grooming following oral administration in vivo.
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