
化学名称 : SB408124/SB-408124/
CAS : 288150-92-5
英文名称: SB408124/SB-408124/
英文同义词: N-(6,8-Difluoro-2-methyl-4-quinolinyl)-N'-[4-(dimethylamino)phenyl]urea
溶解度:Soluble to 100 mM in DMSO
储存条件:Store at RT
生物活性
Selective non-peptide orexin OX1 receptor antagonist (Kb values are 21.7 and 1405 nM for human OX1 and OX2 receptors respectively). Blocks orexin-A induced grooming following oral administration in vivo.
ONO 8711/ONO8711
NNC 756(Odapipam)/
GYKI-52466/
102771-26-6
LY 300168(GYKI 53655)
143692-18-6