141430-65-1
Cat.No.ABP000587
Chemical NameABT-751
MolFormulaC18H17N3O4S
MolWeight371.41
Purity >99%
Chemical Name : ABT-751
CAS : 141430-65-1
Synonyms: N-[2-[(4-Hydroxyphenyl)amino]-3-pyridyl]-4-methoxybenzenesulfonamide
Solubility:DMSO
Storage:at -20
Biologieal
ABT-751 is a bioavailable antimitotic sulfonamide agent that binds to the colchicine-binding site on beta-tubulin and inhibits the polymerization of microtubules, thereby preventing tumor cell replication.Reference
[1] Hande KR et al. Clin Cancer Res. 2006 May 1;12(9):2834-40 [2] Segreti JA et al. Cancer Chemother Pharmacol. 2004 Sep;54(3):273-81 [3] Luo Y et al. Anticancer Drugs. 2009 Jul;20(6):483-92-
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