141430-65-1

溶解度:DMSO

储存条件:at -20

生物活性

ABT-751 is a bioavailable antimitotic sulfonamide agent that binds to the colchicine-binding site on beta-tubulin and inhibits the polymerization of microtubules, thereby preventing tumor cell replication.

参考文献

[1] Hande KR et al. Clin Cancer Res. 2006 May 1;12(9):2834-40 [2] Segreti JA et al. Cancer Chemother Pharmacol. 2004 Sep;54(3):273-81 [3] Luo Y et al. Anticancer Drugs. 2009 Jul;20(6):483-92