PF-04691502
编号ABP000986
化学名称PF-04691502
CAS1013101-36-4
MDL: MFCD18782794
分子式C22H27N5O4
分子量425.486
纯度 >99%
化学名称 : PF-04691502
CAS : 1013101-36-4
英文名称: PF-04691502
英文同义词: 2-Amino-6-(6-methoxypyridin-3-yl)-4-methyl-8-[(1R,4R)-4-(2-hydroxyethoxy)cyclohexyl]-7h,8h-pyrido[2,3-d]pyrimidin-7-one
同义词: 2-Amino-6-(6-methoxypyridin-3-yl)-4-methyl-8-[(1R,4R)-4-(2-hydroxyethoxy)cyclohexyl]-7h,8h-pyrido[2,3-d]pyrimidin-7-one
Solubility:Soluble to 10 mM in DMSO and to 50 mM in ethanol
Storage:Desiccate at +4°C
Biologieal
A selective h5-HT1D antagonist, displaying 60-fold selectivity over h5-HT1B, and exhibiting little or no affinity for a range of other receptor types.Reference
Hagan et al (1997) Stimulation of 5-HT1B receptors causes hypothermia in the rat. Eur.J.Pharmacol. 331 169. PMID: 9274976.-
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