SB939
编号ABP000582
化学名称SB939
CAS929016-96-6
MDL: MFCD17215206
分子式C20H30N4O2
分子量358.483
纯度 >99%
化学名称 : SB939
CAS : 929016-96-6
英文名称: SB939
英文同义词: (2E)-3-(2-Butyl-1-[2-(diethylamino)ethyl]-1h-1,3-benzodiazol-5-yl)-n-hydroxyprop-2-enamide
同义词: (2E)-3-(2-Butyl-1-[2-(diethylamino)ethyl]-1h-1,3-benzodiazol-5-yl)-n-hydroxyprop-2-enamide
Solubility:DMSO to 100 mM
Storage:at -20
Biologieal
Potent and oral inhibitor of histone deacetylase (HDAC), selective for class I, II and IV HDACs. SB939 shows significant antiproliferative activity against a wide variety of tumor cell lines, with high tumor exposure and efficacy in mouse models of colorectal cancer.Reference
V Novotny-Diermary et al. SB939, a novel potent and orally active histone deacetylase inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer. Mol. Cancer Ther. 2010, 9(3), 642-652-
Tralkoxydim
87820-88-0
-
FLUCONAZOLE
86368-73-4
-
GSK256066/
801312-28-7
-
Butoconazole nitrate
64872-77-1
Copyright © 2015-2025 活性医药. All rights reserved. Support by Moldb.
浙公网安备 33010802003999号