SB939
编号ABP000582
化学名称SB939
CAS929016-96-6
MDL: MFCD17215206
分子式C20H30N4O2
分子量358.483
纯度 >99%
化学名称 : SB939
CAS : 929016-96-6
英文名称: SB939
英文同义词: (2E)-3-(2-Butyl-1-[2-(diethylamino)ethyl]-1h-1,3-benzodiazol-5-yl)-n-hydroxyprop-2-enamide
溶解度:DMSO to 100 mM
储存条件:at -20
生物活性
Potent and oral inhibitor of histone deacetylase (HDAC), selective for class I, II and IV HDACs. SB939 shows significant antiproliferative activity against a wide variety of tumor cell lines, with high tumor exposure and efficacy in mouse models of colorectal cancer.参考文献
V Novotny-Diermary et al. SB939, a novel potent and orally active histone deacetylase inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer. Mol. Cancer Ther. 2010, 9(3), 642-652-
盐酸苯达莫司汀
3543-75-7
-
乙酸阿比特龙酯
154229-18-2
-
阿维A
55079-83-9
-
Doripenem Hydrate/Doribax/S-4661/Finibax/
364622-82-2
Copyright © 2015-2025 活性医药. All rights reserved. Support by Moldb.
浙公网安备 33010802003999号