1026785-59-0

主页 / 产品目录 / Inhibitors / Other inhibitors / 1026785-59-0

1026785-59-0

编号ABP000275 化学名称5-(3,3-二甲基-1-丁炔-1-基)-3-[(顺式-4-羟基环己基)[(反式-4-甲基环己基)羰基]氨基]-2-噻吩甲酸 英文名称 VX-222/VX222 MDL: MFCD18089858 分子式C25H35NO4S 分子量445.621 纯度 >99%

产品详情
相关中间体
相关产品

化学名称 : 5-(3,3-二甲基-1-丁炔-1-基)-3-[(顺式-4-羟基环己基)[(反式-4-甲基环己基)羰基]氨基]-2-噻吩甲酸

CAS : 1026785-59-0

英文名称: VX-222/VX222

英文同义词: VX-222

溶解度:Unknown

储存条件:at -20

生物活性

VX-222 (HCV Infection) is a small molecule non-nucleoside inhibitor of HCV NS5B polymerase that is being investigated for the treatment of hepatitis C virus infection. While the protease inhibitors (telaprevir and boceprevir) are the directly-targeted anti-HCV agents furthest along in the development pipeline, HCV polymerase - an enzyme responsible for copying viral genetic material-is also a promising target. VX-222 is a novel non-nucleoside HCV NS5B polymerase inhibitor with potent in vitro activity. [1]

参考文献

[1] 45th Annual Meeting of the European Association for the Study of the Liver (EASL 2010).2010 April 14-18; Vienna, Austria