1026785-59-0

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5-(3,3-二甲基-1-丁炔-1-基)-3-[(顺式-4-羟基环己基)[(反式-4-甲基环己基)羰基]氨基]-2-噻吩甲酸

1026785-59-0

Cat.No.ABP000275 Chemical Name5-(3,3-二甲基-1-丁炔-1-基)-3-[(顺式-4-羟基环己基)[(反式-4-甲基环己基)羰基]氨基]-2-噻吩甲酸 MDL: MFCD18089858 MolFormulaC25H35NO4S MolWeight445.621 Purity >99%

Chemical Name : 5-(3,3-二甲基-1-丁炔-1-基)-3-[(顺式-4-羟基环己基)[(反式-4-甲基环己基)羰基]氨基]-2-噻吩甲酸

CAS : 1026785-59-0

溶解度:Unknown

储存条件:at -20

生物活性

VX-222 (HCV Infection) is a small molecule non-nucleoside inhibitor of HCV NS5B polymerase that is being investigated for the treatment of hepatitis C virus infection. While the protease inhibitors (telaprevir and boceprevir) are the directly-targeted anti-HCV agents furthest along in the development pipeline, HCV polymerase - an enzyme responsible for copying viral genetic material-is also a promising target. VX-222 is a novel non-nucleoside HCV NS5B polymerase inhibitor with potent in vitro activity. [1]

参考文献

[1] 45th Annual Meeting of the European Association for the Study of the Liver (EASL 2010).2010 April 14-18; Vienna, Austria

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