Pyrazofurin

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Pyrazofurin

Pyrazofurin

Cat.No.ABP014531 Chemical NamePyrazofurin CAS30868-30-5 MDL: MFCD00036889 MolFormulaC9H13N3O6 MolWeight259.22 Purity NLT 98%

Chemical Name : Pyrazofurin

CAS : 30868-30-5

Pyrazofurin, a pyrimidine nucleoside analogue with antineoplastic activity, inhibits cell proliferation and DNA synthesis in cells by inhibiting uridine 5'-phosphate (UMP) synthase. Pyrazofurin is an active, sensitive orotate-phosphoribosyltransferase inhibitor with IC50s between 0.06-0.37 µM in the three squamous cell carcinoma (SCC) cell lines Hep-2, HNSCC-14B and HNSCC-14C.
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