SR-4835
Cat.No.ABP013390
Chemical NameSR-4835
CAS2387704-62-1
MolFormula
MolWeight
Purity NLT 98%
Chemical Name : SR-4835
CAS : 2387704-62-1
SR-4835 is a potent, highly selective and ATP competitive dual inhibitor of CDK12/CDK13 (CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM). SR-4835 acts in synergy with DNA-damaging chemotherapy and PARP inhibitors and provokes triple-negative breast cancer (TNBC) cell death.
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