Lurasidone
编号ABP001018
化学名称Lurasidone
CAS367514-87-2
分子式C28H36N4O2S
分子量492.676
纯度 98%
化学名称 : Lurasidone
CAS : 367514-87-2
同义词: (3aR,4S,7R,7aS)-2-[[(1R,2R)-2-[[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione
Biologieal
Potent and selective 5-HT1B/1D receptor antagonist (pKi values are 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptors). Displays > 100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types. Centrally active following oral administration.-
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