Delmopinol

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Delmopinol

Delmopinol

Cat.No.ABP000988 Chemical NameDelmopinol CAS79874-76-3 MDL: MFCD00869129 MolFormulaC16H33NO2 MolWeight271.4387 Purity 98%

Chemical Name : Delmopinol

CAS : 79874-76-3

Synonyms: 2-(3-(4-propylheptyl)morpholino)ethanol

Solubility:DMSO

Storage:at -20℃ 2 years

Biologieal

Selective RAF inhibitor, showing strong selectivity for RAF kinases among a panel of 150 tested kinases; IC50 values: ca 30 nM for BRAF V600E and wild-type CRAF and 100 nM for wild-type BRAF.

Reference

C Montagut et al. Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma. Cancer Res. 2008, 68(12), 4853–4861.
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