
Chemical Name : MK-1775/MK1775
CAS : 955365-80-7
Synonyms: 1,2-Dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-(2-propen-1-yl)-3h-pyrazolo[3,4-d]pyrimidin-3-one
Solubility:DMSO
Storage:at -20℃ 2 years
Biologieal
NVP-BEP800 is a novel, fully synthetic, orally bioavailable inhibitor with an IC50 of 0.058 ± 0.006 μM. It binds to the NH2-terminal ATP-binding pocket of Hsp90. Given the mechanism of action, preclinical activity profile, tolerability, and pharmaceutical properties, NVP-BEP800 is an exciting new oral Hsp90 inhibitor warranting further development. [1][2]
Reference
(24S)-mC 976
112849-14-6
CRILVASTATIN
120551-59-9
IBMX
28822-58-4
C-247
845877-55-6