MDV3100/MDV-3100

Solubility:DMSO

Storage:at -20℃ 2 years

Biologieal

MDV3100 is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. It also induces tumour cell apoptosis, and has no agonist activity.

Reference

[1] Prof Howard I Scher MD et al. The Lancet. 2010 April; 375(9724): 1437-1446