
Chemical Name : VX-222/VX222
CAS : 1026785-59-0
Synonyms: VX-222
Storage:at -20
Biologieal
VX-222 (HCV Infection) is a small molecule non-nucleoside inhibitor of HCV NS5B polymerase that is being investigated for the treatment of hepatitis C virus infection. While the protease inhibitors (telaprevir and boceprevir) are the directly-targeted anti-HCV agents furthest along in the development pipeline, HCV polymerase - an enzyme responsible for copying viral genetic material-is also a promising target. VX-222 is a novel non-nucleoside HCV NS5B polymerase inhibitor with potent in vitro activity. [1]
Reference
[1] 45th Annual Meeting of the European Association for the Study of the Liver (EASL 2010).2010 April 14-18; Vienna, Austria
PF-04971729/PF04971729/
1210344-57-2
ethyl 3-cyclobutylalaninate/
394735-17-2
4,6-Dichloro-1-(1,4-dioxaspiro[4.5]dec-8-yl)-1H-pyrazolo[3,4-d]pyrimidine/
RJR 2403 oxalate
183288-99-5