955365-80-7
编号ABP000952
化学名称MK-1775/MK1775
分子式C27H32N8O2
分子量500.5954
纯度 >99%
化学名称 : MK-1775/MK1775
CAS : 955365-80-7
同义词: 1,2-Dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-(2-propen-1-yl)-3h-pyrazolo[3,4-d]pyrimidin-3-one
Solubility:DMSO
Storage:at -20℃ 2 years
Biologieal
NVP-BEP800 is a novel, fully synthetic, orally bioavailable inhibitor with an IC50 of 0.058 ± 0.006 μM. It binds to the NH2-terminal ATP-binding pocket of Hsp90. Given the mechanism of action, preclinical activity profile, tolerability, and pharmaceutical properties, NVP-BEP800 is an exciting new oral Hsp90 inhibitor warranting further development. [1][2]
Reference
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甲氧沙林
298-81-7
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FMK
821794-92-7
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4'-C-迭氮基胞嘧啶核苷 2',3',5'-三异丁酸酯
690270-29-2
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维塞诺
698394-73-9
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