945619-31-8

Cat.No.ABP000105 Chemical NamePIK75/PIK-75 hydrochloride MolFormulaC16H15BrClN5O4S MolWeight488.743 Purity >99%

Chemical Name : PIK75/PIK-75 hydrochloride

CAS : 945619-31-8

Synonyms: N'-[(1E)-(6-Bromoimidazo[1,2-A]pyridin-3-yl)methylene]-N,2-dimethyl-5-nitrobenzenesulfonohydrazide hydrochloride

Solubility:DMSO

Storage:-20C 2 years

Biologieal

PI3K p110α specific inhibitor; IC50 values (nM): 7.8 (p110α), 343 (p110β), 907 (p110δ) (Chaussade et al reported).

Reference

ZA Knight et al. A Pharmacological Map of the PI3-K Family Defines a Role for p110α in Insulin Signaling. Cell 2006, 125, 733–747.

C Chaussade et al. Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling. Biochem J. 2007, 404(3), 449–458.