878739-06-1

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AZ-628

878739-06-1

Cat.No.ABP000987 Chemical NameAZ-628 MolFormulaC27H25N5O2 MolWeight451.5197 Purity 98%

Chemical Name : AZ-628

CAS : 878739-06-1

Synonyms: 3-(Cyano-dimethyl-methyl)-N-[4-methyl-3-(3-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylamino)-phenyl]-benzamide

Storage:at -20℃ 2 years

Biologieal

Potent, selective, oral and ATP-competitive inhibitor of class I PI3K (Ki: 1-2 nM) and mTOR kinases (Ki: 16 nM); it inhibits PI3K/mTOR signaling and induces cell cycle arrest in cancer cells.
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