878739-06-1
Cat.No.ABP000987
Chemical NameAZ-628
MolFormulaC27H25N5O2
MolWeight451.5197
Purity 98%
Chemical Name : AZ-628
CAS : 878739-06-1
Synonyms: 3-(Cyano-dimethyl-methyl)-N-[4-methyl-3-(3-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylamino)-phenyl]-benzamide
Storage:at -20℃ 2 years
Biologieal
Potent, selective, oral and ATP-competitive inhibitor of class I PI3K (Ki: 1-2 nM) and mTOR kinases (Ki: 16 nM); it inhibits PI3K/mTOR signaling and induces cell cycle arrest in cancer cells.-
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