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Ketorolac Tromethamine


Cat.No.ABP001027 Chemical NameKetorolac Tromethamine MDL: MFCD00887595 MolFormulaC15H13NO3.C4H11NO3 MolWeight376.407 Purity 98%

Chemical Name : Ketorolac Tromethamine

CAS : 74103-07-4

Synonyms: 2-Amino-2-(hydroxymethyl)propane-1,3-diol 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate;KETOROLAC TRIS SALT

Solubility:Soluble to 5 mM in ethanol and to 10 mM in DMSO

Storage:Store at RT


Novel positive allosteric modulator of GABAB receptor function. Potentiates the effects of GABA on [35S]GTPγS binding at recombinant and native GABAB receptors (EC50 values are 2.1 and 3.1μM respectively). Decreases cocaine self-administration, blocks the rewarding properties of nicotine and produces anxiolytic-like activity without the side effects associated with baclofen or benzodiazepines.