74103-07-4
Cat.No.ABP001027
Chemical NameKetorolac Tromethamine
MDL: MFCD00887595
MolFormulaC15H13NO3.C4H11NO3
MolWeight376.407
Purity 98%
Chemical Name : Ketorolac Tromethamine
CAS : 74103-07-4
Synonyms: 2-Amino-2-(hydroxymethyl)propane-1,3-diol 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate;KETOROLAC TRIS SALT
Solubility:Soluble to 5 mM in ethanol and to 10 mM in DMSO
Storage:Store at RT
Biologieal
Novel positive allosteric modulator of GABAB receptor function. Potentiates the effects of GABA on [35S]GTPγS binding at recombinant and native GABAB receptors (EC50 values are 2.1 and 3.1μM respectively). Decreases cocaine self-administration, blocks the rewarding properties of nicotine and produces anxiolytic-like activity without the side effects associated with baclofen or benzodiazepines.-
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