Chemical Name : Diclofensine(Ro 8-4650)/
CAS : 67165-56-4
Synonyms: DICLOFENSINE
Solubility:Soluble to 100 mM in DMSO
Storage:Store at RT
Biologieal
Potent, selective inhibitor of the reverse mode of the Na+/Ca2+ exchanger (IC50 = 0.7 mM). Also inhibits the mitochondrial Ca2+ uniporter (MCU; IC50 = 5.5 μM). Does not affect Na+-dependent transport systems or ionotropic glutamate receptors.