541550-19-0

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STA 5326

541550-19-0

Cat.No.ABP000484 Chemical NameSTA 5326 MDL: MFCD09954108 MolFormulaC23H26N6O2 MolWeight418.498 Purity 98%

Chemical Name : STA 5326

CAS : 541550-19-0

Synonyms: APILIMOD

Storage:at -20℃ 2 years

Biologieal

Potent and orally active inhibitor of the cytokines interleukin-12 (IL-12), and interleukin-23 (IL-23) production; potential regulators of certain autoimmune and inflammatory diseases.

Reference

Wada et al: Selective abrogation of Th1 response by STA-5326, a potent IL-12/IL-23 inhibitor. Blood, 2007, 109(3), 1156-1164. Wada et al: IL-12/IL-23 inhibitors: a promising approach to the treatment of inflammatory disorders. Drugs Fut. 2008, 33(1), 49-63.

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