Chemical Name : BAN ORL 24HCL
CAS : 475150-69-7
Synonyms: (2R)-1-Benzyl-N-(3-spiro[isobenzofuran-1(3H),4'-piperidin]-1'-ylpropyl)-2-pyrrolidinecarboxamide
Solubility:H2O, DMSO and EtOH
Storage:at -20℃ 2 years
Biologieal
Highly potent and selective NOP receptor antagonist (IC50: 0.27 nM); more than 2500 fold selective over other opioid receptorsReference
Y Goto et al. Identification of a novel spiropiperidine opioid receptor-like 1 antagonist class by a focused library approach featuring 3D-pharmacophore similarity. J. Med. Chem. 2006, 49 847-849.