Cat.No.ABP000274 Chemical NameBIBR-1532/BIBR1532 MDL: MFCD11112195 MolFormulaC21H17NO3 MolWeight331.369 Purity >98 %

Chemical Name : BIBR-1532/BIBR1532

CAS : 321674-73-1

Synonyms: BIBR 1532

Solubility:Soluble to 100 mM in DMSO and to 25 mM in ethanol

Storage:Store at RT


Selective telomerase inhibitor (IC50 values are 93, > 100000 and > 100000 nM for human telomerase, human RNA polymerase I and human RNA polymerase II + III respectively). Causes telomere shortening in exponentially growing NCI-H460 lung carcinoma cells and eventual growth arrest.


Damm et al (2001) A highly selective telomerase inhibitor limiting human cell proliferation. EMBO J. 20 6958. Phatak and Burger (2007) Telomerase and its potential for therapeutic intervention. Br.J.Pharmacol. 152 1003. Rankin et al (2008) Telomerase inhibitors and 'T-oligo' as caner therapeutics: contrasting molecular mechanisms of cytotoxicity. Anticancer Drugs 19 329.