18274-81-2

Desmethylanethol Trithione is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. ADT is a putative neuroprotectant and antioxidant that increases glutathione levels in cultured astroglial cells. ADT-OH was shown to reduce tPA-enhanced Akt activation and VEGF expression in brain microvascular endothelial cells.