146464-95-1

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Pralatrexate(Folotyn)/

146464-95-1

编号ABP000543 化学名称Pralatrexate(Folotyn)/ MDL: MFCD00920897 分子式C23H23N7O5 分子量477.479 纯度 >99%

化学名称 : Pralatrexate(Folotyn)/

CAS : 146464-95-1

同义词: 10-PROPARGYL-10-DEAZAAMINOPTERIN

Storage:at -20℃ 2 years

Biologieal

Pralatrexate is an antifolate, and structurally a folate analog. It acts as an inhibitor of dihydrofolate reductase. It is selective for the reduced folate carrier type 1. Its IC50 is < 300 nM in some cell lines. [1]

Reference

[1] http://en.wikipedia.org/wiki/Pralatrexate

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