1346168-57-7

Soluble in DMSO or ethanol. CEP-33779 is a highly selective, orally active inhibitor for JAK2 with an IC(50) of 1.8nM in enzyme and 61nM in cell activity. It inhibits JAK3 with an IC(50) of 150nM. Target: JAK | Kinase Group: PTK | Substrate: Tyrosine