1262036-50-9

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LY2886721/LY-2886721/

1262036-50-9

Cat.No.ABP000957 Chemical NameLY2886721/LY-2886721/ MDL: MFCD21609263 MolFormulaC18H17FN4O2S MolWeight372.422 Purity >98%

Chemical Name : LY2886721/LY-2886721/

CAS : 1262036-50-9

Synonyms: LY2886721

Storage:at -20℃ 2 years

Biologieal

AZD8330 (RRY-424704,ARRY-704) is an orally active, selective MEK inhibitor with an IC50 of 7 nM. AZD8330 (RRY-424704,ARRY-704) has potential antineoplastic activity. AZD8330 (RRY-424704,ARRY-704) specifically inhibits mitogen- activated protein kinase kinase 1 (MEK or MAP/ERK kinase1), resulting in inhibition of growth factor-mediated cell signaling and tumor cell proliferation. MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that regulates cell growth. Constitutive activation of this pathway has been implicated in many cancers. [1][2]

Reference

[1] http://www.cancer.gov/drugdictionary/?CdrID=543526

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