Chemical Name : BIX 02189/BIX02189
CAS : 1094614-85-3
Synonyms: 3-[[[3-[(Dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-N,N-dimethyl-2-oxo-1H-indole-6-carboxamide
Solubility:Soluble in DMSO at 20 mg/mL
Storage:Storage at -20C 2 years
Biologieal
A MEK5-selective inhibitor, completely reversed the inhibitory effects of flow.
Reference
ERK5 Activity Is Required for Nerve Growth Factor-induced Neurite Outgrowth and Stabilization of Tyrosine Hydroxylase in PC12 Cells Identification of pharmacological inhibitors of the MEK5/ERK5 pathway.