101-26-8

Pyridostigmine Bromide/Mestinon

101-26-8

Cat.No.ABP000290 Chemical NamePyridostigmine Bromide/Mestinon MDL: MFCD00079283 MolFormulaC9H13N2O2.Br MolWeight261.118 Purity >99%

Chemical Name : Pyridostigmine Bromide/Mestinon

CAS : 101-26-8

Synonyms: PYRIDOSTIGMINE BROMIDE

Storage:at -20℃ 2 years

Biologieal

Pyridostigmine Bromide(Mestinon) is a parasympathomimetic and a reversible cholinesterase inhibitor. Pyridostigmine Bromide inhibits acetylcholinesterase in the synaptic cleft, thus slowing down the hydrolysis of acetylcholine. It is a quaternary carbamate inhibitor of cholinesterase that does not cross the blood-brain barrier, and it is taken daily in anticipation of an attack, which carbamylates about 30% of peripheral cholinesterase enzyme. The carbamylated enzyme eventually regenerates by natural hydrolysis and excess ACh levels revert to normal. [1]

Reference

[1] http://en.wikipedia.org/wiki/Pyridostigmine

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