巴瑞替尼
编号ABP001023
化学名称INCB 028050
CAS1187594-09-7
分子式C16H17N7O2S
分子量371.417
纯度 98%
化学名称 : 巴瑞替尼
CAS : 1187594-09-7
英文名称: INCB 028050
英文同义词: 2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile
生物活性
Potent, irreversible human epithelial growth factor receptor 2 (ErbB2) inhibitor (IC50 = 6 nM) that displays > 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src. Exhibits potent antiproliferative effects in ErbB2-overexpressing cancer cell lines (IC50 = 5 nM in BT474 breast cancer cells) and significantly inhibits bladder, breast and prostate cancer xenograft growth in vivo.-
NVP-BKM-120
944396-07-0
-
尼替西农
104206-65-7
-
Bencynoate hydrochloride/
162220-36-2
-
3-(2,4-二羟基-5-异丙基苯基)-4-(1-甲基吲哚-5-基)-5-羟基-4H-1,2,4-噻唑
888216-25-9
Copyright © 2015-2025 活性医药. All rights reserved. Support by Moldb.
浙公网安备 33010802003999号