A-803467

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A-803467

A-803467

编号ABP001000 化学名称A-803467 CAS944261-79-4 分子式C19H16ClNO4 分子量357.788 纯度 98%

化学名称 : A-803467

CAS : 944261-79-4

英文名称: A-803467

英文同义词: 5-(4-Chlorophenyl)-N-(3,5-dimethoxy phenyl)-2-furancarboxamide

同义词: 5-(4-Chlorophenyl)-N-(3,5-dimethoxy phenyl)-2-furancarboxamide

Storage:Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO

Biologieal

Highly selective α7 nAChR agonist (Ki = 26 nM) displaying negligible blockade of α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM). Found to be inactive against a panel of 32 receptors at 1 μM, except 5-HT3 receptors (Ki = 930 nM).
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