马尼地平二盐酸盐
编号ABP000987
化学名称AZ-628
CAS878739-06-1
分子式C27H25N5O2
分子量451.5197
纯度 98%
化学名称 : 马尼地平二盐酸盐
CAS : 878739-06-1
英文名称: AZ-628
英文同义词: 3-(Cyano-dimethyl-methyl)-N-[4-methyl-3-(3-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylamino)-phenyl]-benzamide
储存条件:at -20℃ 2 years
生物活性
Potent, selective, oral and ATP-competitive inhibitor of class I PI3K (Ki: 1-2 nM) and mTOR kinases (Ki: 16 nM); it inhibits PI3K/mTOR signaling and induces cell cycle arrest in cancer cells.-
MLN9708
1201902-80-8
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