Fadrozole hydrochloride

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Fadrozole hydrochloride

Fadrozole hydrochloride

编号ABP000972 化学名称Fadrozole hydrochloride CAS102676-31-3 MDL: MFCD00866239 分子式C14H14ClN3 分子量259.734 纯度 ≥98%

化学名称 : Fadrozole hydrochloride

CAS : 102676-31-3

英文名称: Fadrozole hydrochloride

英文同义词: 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile hydrochloride

同义词: 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile hydrochloride

Storage:at -20℃ 2 years

Biologieal

Acitazanolast is an active metabolite of tazanolast and anti-allergic drug. In a study, pretreatment with topical instillation of acitazanolast hydrate inhibited the dye leakage significantly. In the histopathological observation, acitazanolast hydrate ophthalmic solution also improved the inflammatory score and reduced the infiltration of inflammatory cells such as neutrophil and eosinophil in conjunctiva markedly. These anti-allergic effects of acitazanolast hydrate ophthalmic solution were equal to those of levocabastine and ketotifen. From these results, it is suggested that acitazanolast hydrate ophthalmic solution is a promising ophthalmic solution for treatment of allergic conjunctivitis. [1]

Reference

1] http://sciencelinks.jp/j-east/article/200211/000020021102A0336439.php

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