Flavopiridol(Alvocidib)/HMR-1275,L868275

Storage:at -20℃ 2 years

Biologieal

AT7519 is a novel small molecule multi-cyclin-dependent kinase inhibitor. It selectively binds to and inhibits cyclin dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation. CDKs are serine/theronine kinases involved in regulation of the cell cycle and may be overexpressed in some types of cancer cells. [1][2]

Reference

[1] Santo L et al. Oncogene. 2010 Apr 22;29(16):2325-36