Atazanavir(BMS-232632)/Reyataz
化学名称 : Atazanavir(BMS-232632)/Reyataz
CAS : 198904-31-3
英文名称: Atazanavir(BMS-232632)/Reyataz
英文同义词: 3,12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-, 1,14-dimethyl ester, (3s,8s,9s,12s)-2,5,6,10,13-pentaazatetradecanedioic acid;ATAZANAVIR
同义词: 3,12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-, 1,14-dimethyl ester, (3s,8s,9s,12s)-2,5,6,10,13-pentaazatetradecanedioic acid;ATAZANAVIR
Storage:at -20℃ 2 years
Biologieal
Atazanavir (Reyataz, BMS-232632) is an antiretroviral drug of the protease inhibitor (PI) class. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus (HIV). Atazanavir is distinguished from other PIs in that it can be given once-daily (rather than requiring multiple doses per day) and has lesser effects on the patient's lipid profile (the amounts of cholesterol and other fatty substances in the blood). Like other protease inhibitors, it is used only in combination with other HIV medications. [1]
Reference
P Pyrko. HIV-1 protease inhibitors nelfinavir and atazanavir induce malignant glioma death by triggering endoplasmic reticulum stress. Cancer Research 2007, 67, 10920
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