Aprepitant(MK-0869)
编号ABP000600
化学名称Aprepitant(MK-0869)
CAS170729-80-3
分子式C23H21F7N4O3
分子量534.4267
纯度 >99%
化学名称 : Aprepitant(MK-0869)
CAS : 170729-80-3
英文名称: Aprepitant(MK-0869)
英文同义词: 5-[[(2R,3S)-2-[(1R)-1-[3,5-BIS(Trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one
溶解度:Unknown
储存条件:at -20℃ 2 years
生物活性
Aprepitant is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA). It mediates its effect by blocking the neurokinin 1 (NK1) receptor. Aprepitant is used for prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) and for prevention of postoperative nausea and vomiting.[1]
参考文献
[1] http://en.wikipedia.org/wiki/Aprepitant
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PD-173955
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1-[1-(1-甲基环辛基)-4-哌啶基]-2-[(3R)-3-哌啶基]-1H-苯并咪唑
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